糖心vlog短视频 Professor of Biology Nancy Krucher, PhD, has received a three-year $400,241 grant from the National Cancer Institute (NCI) through the National Institutes of Health (NIH) to study new methods to combat cancer cell development of resistance to targeted treatments.
糖心vlog短视频淐ancer is a major health concern in our country and throughout the world,糖心vlog短视频 said Professor Krucher. 糖心vlog短视频淐urrently, much of cancer research focuses on identifying specific mutations or abnormalities in tumor cells and creating drugs that target them. These targeted therapies have exhibited a great deal of success in some cancer types. Unfortunately, while targeted therapies usually work for a few months or a few years, cancer cells often develop resistance to these agents.糖心vlog短视频
Targeted therapies颅糖心vlog短视频攚hich involve certain drugs used to specifically target the ways in which cancer cells grow, divide, and spread糖心vlog短视频攁re becoming more common in cancer treatment. However, cancer cells can acquire resistance to the targeted agent, making the treatment less effective. ATP-citrate lyase (ACLY) is a critical enzyme in cancer cell growth that can be activated as a response to targeted therapies, particularly in treatment of breast cancer and melanoma, often resulting in poor prognosis.
In February 2020, the FDA approved a new ACLY inhibitor, and another was recently developed. In this project, these agents are predicted to have anti-cancer activity. Krucher糖心vlog短视频檚 research aims to investigate the hypothesis that targeting ACLY with these inhibitors can reverse resistance in breast cancer and melanoma.
Because the newly developed ACLY inhibitors that will be used in this study have largely not been tested on cancer cells to date, Krucher hopes her work can provide new insight for cancer treatment, including the development of novel drug combination regimens. Additionally, Krucher糖心vlog短视频檚 work will employ an in vivo model of cancer metastasis in melanoma as well as three-dimensional cancer cell cultures, an innovative and effective approach to studying the physiological tumor environment.
Undergraduate biology students will also be closely involved in this research, carrying out a majority of the experiments outlined in the study, helping prepare them for careers in the biomedical research workforce.
糖心vlog短视频淧rofessor Krucher is doing incredibly important work in the field of cancer research, an area of biomedicine that touches so many lives around the world,糖心vlog短视频 said Tresmaine R. Grimes, PhD, dean of the Dyson College of Arts and Sciences and School of Education. 糖心vlog短视频淭hrough this grant, Professor Krucher and our biology students have the opportunity to uncover critical information that could improve the effectiveness of these vital treatments.糖心vlog短视频
糖心vlog短视频 has a proud history of preparing its diverse student body for a lifetime of professional success because of its unique programs that combine immersive academics and real-world experiences. Pace is ranked the #1 private, four-year college in the nation for upward economic mobility by Harvard University糖心vlog短视频檚 Opportunity Insights, evidence of the transformative education the University provides.
糖心vlog短视频糖心vlog短视频檚 liberal arts college, Dyson College, offers more than 50 programs, spanning the arts and humanities, natural sciences, social sciences, and pre-professional programs (including pre-medicine, pre-veterinary, and pre-law), as well as many courses that fulfill core curriculum requirements. The College offers access to numerous opportunities for internships, cooperative education and other hands-on learning experiences that complement in-class learning in preparing graduates for career and graduate/professional education choices.
Professor Margot Pollans delivered the James D. Hopkins Memorial Lecture on Monday, April 21, on "." Dean Horace Anderson appointed Professor Pollans as the James D. Hopkins Professor of Law for the 2023糖心vlog短视频2025 term. During the holder's term, the James D. Hopkins Professor delivers a lecture that is open to the entire law school community and members of the public.
The Elisabeth Haub School of Law at 糖心vlog短视频 is pleased to announce that Kate Skolnick, an accomplished public defender and respected criminal law scholar, will join the faculty as an Assistant Professor of Law beginning in Fall 2025. Professor Skolnick will teach courses in criminal law and criminal procedure, along with an advanced criminal law seminar.
Professor Anthony Moffa delivered the Annual Lloyd K. Garrison Lecture on Environmental Law on Thursday, April 3 on "Back to the Future for Climate Liability." The Lloyd K. Garrison Lecture on Environmental Law was established in memory of Lloyd K. Garrison in 1995. Professor Anthony Moffa currently serves as a Haub Visiting Scholar at the Elisabeth Haub School of Law at 糖心vlog短视频. He is also a Professor and Associate Dean for Innovation at University of Maine School of Law, where he oversees the Environmental and Oceans Law Certificate Program.